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Before getting licensed to drive a cab in London, a person has to pass an incredibly difficult test with an intimidating name ─ "The Knowledge." The test involves memorizing the layout of more than 20,000 streets in the Greater London area - a feat that involves an incredible amount of memory resources. In fact, fewer than 50 percent of the people who sign up for taxi driver training pass the test, even after spending two or three years studying for it! And as it turns out, the brains of London cabbies are different from non-cab-driving humans in ways that reflect their herculean memory efforts. In fact, the part of the brain that has been most frequently associated with spatial memory, the tail of the sea horse-shaped brain region called the hippocampus, is bigger than average in these taxi drivers.

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When evaluating a policy, people tend to concentrate on how the policy will fix some particular problem while ignoring or downplaying other effects it may have. Economists often refer to this situation as The Law of Unintended Consequences. For instance, suppose that you impose a tariff on imported steel in order to protect the jobs of domestic steelworkers. If you impose a high enough tariff, their jobs will indeed be protected from competition by foreign steel companies. But an unintended consequence is that the jobs of some autoworkers will be lost to foreign competition. Why? The tariff that protects steelworkers raises the price of the steel that domestic automobile makers need to build their cars. As a result, domestic automobile manufacturers have to raise the prices of their cars, making them relatively less attractive than foreign cars. Raising prices tends to reduce domestic car sales, so some domestic autoworkers lose their jobs.

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Species that are found in only one area are called endemic species and are especially vulnerable to extinction. They exist on islands and in other unique small areas, especially in tropical rain forests where most species are highly specialized. One example is the brilliantly colored golden toad once found only in a small area of lush rain forests in Costa Rica's mountainous region. Despite living in the country's well-protected Monteverde Cloud Forest Reserve, by 1989, the golden toad had apparently become extinct. Much of the moisture that supported its rain forest habitat came in the form of moisture-laden clouds blowing in from the Caribbean Sea. But warmer air from global climate change caused these clouds to rise, depriving the forests of moisture, and the habitat for the golden toad and many other species dried up. The golden toad appears to be one of the first victims of climate change caused largely by global warming.

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The fundamental nature of the experimental method is manipulation and control. Scientists manipulate a variable of interest, and see if there's a difference. At the same time, they attempt to control for the potential effects of all other variables. The importance of controlled experiments in identifying the underlying causes of events cannot be overstated. In the real-uncontrolled-world, variables are often correlated. For example, people who take vitamin supplements may have different eating and exercise habits than people who don't take vitamins. As a result, if we want to study the health effects of vitamins, we can't merely observe the real world, since any of these factors (the vitamins, diet, or exercise) may affect health. Rather, we have to create a situation that doesn't actually occur in the real world. That's just what scientific experiments do. They try to separate the naturally occurring relationship in the world by manipulating one specific variable at a time, while holding everything else constant.

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Why do people in the Mediterranean live longer and have a lower incidence of disease? Some people say it's because of what they eat. Their diet is full of fresh fruits, fish, vegetables, whole grains, and nuts. Individuals in these cultures drink red wine and use great amounts of olive oil. Why is that food pattern healthy? One reason is that they are eating a palette of colors. More and more research is surfacing that shows us the benefits of the thousands of colorful "phytochemicals"(phyto=plant) that exist in foods. These healthful, non‑nutritive compounds in plants provide color and function to the plant and add to the health of the human body. Each color connects to a particular compound that serves a specific function in the body. For example, if you don't eat purple foods, you are probably missing out on anthocyanins, important brain protection compounds. Similarly, if you avoid green‑colored foods, you may be lacking chlorophyll, a plant antioxidant that guards your cells from damage.

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